Recombinant MS4A1 (Rituximab Biosimilar) antibody

Catalog No. ABIN7795085

This Mouse Monoclonal antibody specifically detects MS4A1 (Rituximab Biosimilar) in FACS and in vivo. It exhibits reactivity toward Human.

Quick Overview for Recombinant MS4A1 (Rituximab Biosimilar) antibody (ABIN7795085)

Target: MS4A1 (Rituximab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MS4A1 (Rituximab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade: Research Grade

Product Details anti-MS4A1 (Rituximab Biosimilar) Antibody

Expression System: Mammalian cells

Purpose: Rituximab Biosimilar, Endotoxin 0.05 EU/mg

Characteristics: B-lymphocyte antigen CD20 encoded by the MS4A1 gene is an activated-glycosylated phosphoprotein on the surface of all B-cells. The function of the membrane protein is to stimulate B-cell immune response, specifically against T-independent antigens though its natural ligand remains unknown. CD20 is important for the development and differentiation of B-cells into plasma cells. CD20 belongs to the membrane-spanning 4A family with common structural features, similar intron/exon splice boundaries, and unique expression patterns among hematopoietic cells and nonlymphoid tissues. Rituximab, a chimeric anti-CD20 monoclonal antibody, destroys B cells and is used to treat diseases with excessive numbers of B cells, overactive B cells, or dysfunctional B cells, such as many lymphomas, leukemias, transplant rejection, and autoimmune disorders.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: Less than 0.5 EU/mg of protein as determined by LAL method

Immunogen: Human lymphoblastoid cell line SB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for MS4A1 (Rituximab Biosimilar)

Target: MS4A1 (Rituximab Biosimilar)

Alternative Name: Rituximab Biosimilar

Target Type: Biosimilar